HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3,4-Dimethoxyphenyl)acetyl chloride → 6-(3,4-Dimethoxy-benzyl)-1-[1-(1-hydroxy-ethyl)-4-phenyl-butyl]-1,5-dihydro-pyrazolo-[3,4-d]pyrimidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3,4-Dimethoxyphenyl)acetyl chloride | HCID 3604458 | — |
| Reactant | 5-Amino-1-[1-(1-hydroxy-ethyl)-4-phenyl-butyl]-1H-pyrazole-4-carboxamide | HCID 21266078 | — |
| Product | 6-(3,4-Dimethoxy-benzyl)-1-[1-(1-hydroxy-ethyl)-4-phenyl-butyl]-1,5-dihydro-pyrazolo-[3,4-d]pyrimidin-4-one | HCID 135702876 | — |
Reaction Steps
Starting from 400 mg (1.32 mmol) of 5-amino-1-[1-(1-hydroxy-ethyl)-4-phenyl-butyl]-1H-pyrazol-4-carboxamide and 711 mg (3.32 mmol) of 3,4-dimethoxyphenylacetylchloride, the title compound is obtained analogously to the protocol of Example 13.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06174884B1 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-8cf9e19ebec3430c822e5f8a2cc92847 |
| Source note | uspto-grants-2001_01 |