Methyl 2-(1,3-dioxaindan-5-yl)acetate → HCID 135702883, compound

Participants

Reaction Steps

18 mg (0.066 mmol) of 5-amino-1-(1-methyl-4-phenyl-butyl)-1H-pyrazole-4-carboxamide and 41 mg (0.21 mmol) of methyl 3,4-methylenedioxyphenylacetate are refluxed for 6 hours in 1 ml of a 0.5M ethanolic potassium tert-butoxide solution. After dichloromethane and saturated aqueous sodium hydrogen carbonate solution have been added, the phases are separated. Purification by chromatography gives 18 mg (64%) of a solid, Rf=0.34 (dichloromethane/methanol=15:1).

Provenance & Evidence