Sodium Bicarbonate → HCID 136132161, compound

Participants

Reaction Steps

10 mg (0.02 mmol) of 5-amino-3-ethyl-1-(4-decyl)-1H-pyrazole-4-carboxamide and 20 mg (0.091 mmol) of methyl 3,4-dichlorophenylacetate are refluxed for 6 hours in 0.3 ml of a 0.5M ethanolic sodium ethoxide solution. After dichloromethane and saturated aqueous sodium hydrogen carbonate solution have been added, the phases are separated. Purification by chromatography gives 4 mg (45%) of a solid, Rf=0.67 (dichloromethane/methanol=15:1).

Provenance & Evidence