Methyl 2-(4-bromophenyl)acetate → HCID 136132144, compound

Participants

Reaction Steps

10 mg (0.034 mmol) of 5-amino-3-ethyl-1-(4-decyl)-1H-pyrazole-4-carboxamide and 20 mg (0.087 mmol) of methyl 4-bromophenylacetate are refluxed for 6 hours in 0.3 ml of a 0.5M ethanolic sodium ethoxide solution. After dichloromethane and saturated aqueous sodium hydrogen carbonate solution have been added, the phases are separated. Purification by chromatography gives 7 mg (67%) of a solid, Rf=0.69 (dichloromethane/methanol=15:1).

Provenance & Evidence