Benzeneacetic acid, 3,4-dimethoxy-, methyl ester → HCID 136132171, compound

Participants

Reaction Steps

6 mg (0.02 mmol) of 5-amino-3-ethyl-1-(4-decyl)-1H-pyrazole-4-carboxamide and 20 mg (0.095 mmol) of methyl 3,4-dimethoxyphenylacetate are refluxed for 6 hours in 0.3 ml of a 0.5M ethanolic potassium tert-butoxide solution. After dichloromethane and saturated aqueous sodium hydrogen carbonate have been added, the phases are separated. Purification by chromatography gives 4 mg (42%) of a solid, Rf=0.47 (dichloromethane/methanol=15:1).

Provenance & Evidence