6-Nitro-2-(phenylmethyl)-1H-benzimidazole → HCID 178507350, compound
Reaction equation
[N+:1]([C:4]1[CH:19]=[CH:18][C:7]2[N:8]=[C:9]([CH2:11][C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[NH:10][C:6]=2[CH:5]=1)([O-])=O.NC1C=C2C(=CC=1)N(CC1C=CC=CC=1)C=C2>>[NH2:1][C:4]1[CH:19]=[CH:18][C:7]2[NH:8][C:9]([CH2:11][C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[N:10][C:6]=2[CH:5]=1Participants
3
Procedure
The title compound was prepared from 5-nitro-2-benzylbenzimidazole by an analogous reduction method to that described above for 5-amino-1benzyl-1H-indole; m/z (M+1)+224. Also note the published method (J. Het. Chem., 23, 1109-13, (1986)).
Sources & evidence
- ORD record
- ord-4159512a478e4dd6aa23097dc2e66d00
- Source dataset
- uspto-grants-2001_01
- Patent number
- US06174889B1
Reaction notes
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