HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 566384Generated: October 30, 2026
Dimethylamine → 6-(N,N-Dimethylamino)-3H-pyrido[3,4-d]pyrimidin-4-one
https://huagongshe.com/reaction/566384
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 6-chloro-3H,4H-pyrido[3,4-d]pyrimidin-4-one | HCID 135480525 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6-(N,N-Dimethylamino)-3H-pyrido[3,4-d]pyrimidin-4-one | HCID 135817446 | — |
Reaction Steps
Alternatively, 6-chloro-pyrido[3,4-d]pyrimidin-4-one (26.14 g) was treated with 2N dimethylamine in ethanol (200 ml) and heated at 130° C. in a Parr bomb for 3 days. The cooled mixture was filtered and triturated from isopropanol to give the title compound (16.61 g) as a yellow solid; m/z (M+1+)191.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06174889B1 |
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| Source dataset | uspto-grants-2001_01 |
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| ORD ID | ord-c30579f265934d4b8d189d1c0f31587a |
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| Source note | uspto-grants-2001_01 |
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