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HRID56639

反应详情

EQUATION

反应方程式

HRID 56639 的结构方程式

REACTANTS

反应物

2
结构：CC(Br)C(=O)OC(C)(C)C
HCID545327

tert-Butyl 2-bromopropanoate

C7H13BrO2

结构：C[Si](C)(C)C#Cc1ccc(Cl)cc1-c1cc[nH]c(=O)c1
HCID123837260

未命名化合物

PRODUCTS

生成物

1
结构：CC(C(=O)OC(C)(C)C)n1ccc(-c2cc(Cl)ccc2C#C[Si](C)(C)C)cc1=O
HCID123454309

未命名化合物

PROCEDURE

实验过程

125 mg (purity 91%, 0.38 mmol) of 4-{5-chloro-2-[(trimethylsilyl)ethynyl]phenyl}pyridin-2(1H)-one and 1.2 eq. of tert-butyl 2-bromopropanoate (racemate) were reacted at 80° C. according to General Method 4B. Yield: 56 mg (purity 89%, 31% of theory)