1-(3-Fluorobenzyl)-1H-indazol-5-amine → HCID 9824983, compound

HRID 566400Notes

Reaction equation

HRID 566400 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][CH:18]=1)[CH2:5][N:6]1[C:14]2[C:9](=[CH:10][C:11]([NH2:15])=[CH:12][CH:13]=2)[CH:8]=[N:7]1.[Cl:19][C:20]1[C:21]2[CH:29]=[C:28]([N:30]([CH3:32])[CH3:31])[N:27]=[CH:26][C:22]=2[N:23]=[CH:24][N:25]=1>>[ClH:19].[F:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][CH:18]=1)[CH2:5][N:6]1[C:14]2[C:9](=[CH:10][C:11]([NH:15][C:20]3[C:21]4[CH:29]=[C:28]([N:30]([CH3:32])[CH3:31])[N:27]=[CH:26][C:22]=4[N:23]=[CH:24][N:25]=3)=[CH:12][CH:13]=2)[CH:8]=[N:7]1

Participants

3

Reactant 2

HCID 71470731-(3-Fluorobenzyl)-1H-indazol-5-amineHCID 227274534-Chloro-6-(N,N-dimethylamino)-pyrido[3,4-d]pyrimidine

Product 1

HCID 9824983HCID 9824983, compound

Procedure

Prepared according to Procedure A from 1-(3-Fluoro-benzyl)-1H-indazol-5-ylamine and 4-chloro-6-(N,N-dimethylamino)-pyrido[3,4-d]pyrimidine; δH [2H6]DMSO 11.52 (1H,s), 8.90(1H,s), 8.60(1H,s), 8.24(1H,s), 8.14(1H,s), 7.85(2H,m), 7.70(1H,d), 7.49(1H,s) 7.10(3H,m), 5.72(2H,s), 3.19(6H,s); m/z (M+1+) 414.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d1f62784a0a441e48cdc8736eba44dda
Source dataset
uspto-grants-2001_01
Patent number
US06174889B1

Reaction notes

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