HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic acid, 4-amino-, 1,1-dimethylethyl ester → Tert-butyl 4-(2-(4-(2,5-dichlorophenyl)-2-oxopyridin-1(2h)-yl)propanamido)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic acid, 4-amino-, 1,1-dimethylethyl ester | HCID 233272 | — |
| Reactant | 2-[4-(2,5-Dichlorophenyl)-2-oxopyridin-1(2H)-yl]propanoic acid | HCID 117622564 | — |
| Product | Tert-butyl 4-(2-(4-(2,5-dichlorophenyl)-2-oxopyridin-1(2h)-yl)propanamido)benzoate | HCID 117622667 | — |
Reaction Steps
117 mg (0.36 mmol) of 2-[4-(2,5-dichlorophenyl)-2-oxopyridin-1(2H)-yl]propanoic acid (racemate) and 1.2 eq. of tert-butyl 4-aminobenzoate were reacted according to General Method 5A. Yield: 83 mg (47% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434690B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-7a827b9686aa4e8e877af8c33ecb9ff5 |
| Source note | uspto-grants-2016_09 |