HCID 10697072, compound → HCID 9957361, compound

Participants

Reaction Steps

A stirring solution of (RS) 1-[N-(2-methoxybenzyl)amino]-3-(1H-indol-3-yl)-2-[N-(2-((4-phenyl)piperazin-1-yl)acetyl)amino]propane (50 mg, 0.098 mmol), prepared as described in Preparation 4, supra, dissolved in 6 ml of 1,2-dichlorobenzene was heated to reflux under a nitrogen atmosphere. The solution was allowed to reflux overnight. The progress of the reaction was monitored by thin layer chromatography. The solution was then refluxed for an additional eight hours. The desired title product was then purified by chromatography. (Yield: 40.0 mg, 83%).

Provenance & Evidence