HuagongsheHuagongshe Chemistry Print Report · For research reference only
3(RS)-(3-Biphenyl-4-yl-1H-imidazol-1-yl)-N-(hexahydroazepin-2-on-3(S)-yl]succinamic Acid Benzyl Ester → 3(RS)-(3-biphenyl-4-yl-1H-imidazol-1-yl)-N-(hexahydroazepin-2-on-3(S)-yl)succinamic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3(RS)-(3-Biphenyl-4-yl-1H-imidazol-1-yl)-N-(hexahydroazepin-2-on-3(S)-yl]succinamic Acid Benzyl Ester | HCID 53846884 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3(RS)-(3-biphenyl-4-yl-1H-imidazol-1-yl)-N-(hexahydroazepin-2-on-3(S)-yl)succinamic acid | HCID 18341321 | 94% |
Reaction Steps
According to the procedure described in Example 1(a), a suspension of 3(RS)-(3-biphenyl-4-yl-1H-imidazol-1-yl)-N-(hexahydroazepin-2-on-3(S)-yl)succinamic acid benzyl ester in EtOH was hydrogenolyzed after 90 minutes to provide 779 mg (94%) of 3(RS)-(3-biphenyl-4-yl-1H-imidazol-1-yl)-N-(hexahydroazepin-2-on-3(S)-yl)succinamic acid as a solid. FABMS: 447 (C25H27N4O4; M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06174915B1 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-0204a94c4bf6465b945049d30816cdb2 |
| Source note | uspto-grants-2001_01 |