反应详情

A solution of 20 g (133 mole) of 4,6,6-trimethyl-1,3-cyclohexadiene-1-carbaldehyde in 100 ml of diethylether was added to a suspension of 1.5 g (39 mmole) of LiAlH4 in diethylether, under stirring and cooling with an ice-bath. After 1 h of reaction time, the mixture was hydrolyzed, the organic layer was separated, washed and dried and concentrated. The crude product was then distilled in vacuo, b.p. 60°/20 hPa, to obtain 11.6 g (56%) of the desired product.

1. temperaturecooling with an ice-bath
2. customAfter 1 h of reaction time
3. customthe organic layer was separated
4. washwashed
5. customdried
6. concentrationconcentrated
7. distillationThe crude product was then distilled in vacuo, b.p. 60°/20 hPa