Aluminium lithium hydride → HCID 21263744, compound

HRID 566854Notes

Reaction equation

HRID 566854 reaction equation
[CH3:1][C:2]1([CH3:11])[CH2:7][CH:6]([CH3:8])[CH2:5][CH2:4][CH:3]1[CH:9]=[O:10].[H-].[H-].[H-].[H-].[Li+].[Al+3]>C(OCC)C>[CH3:11][C:2]1([CH3:1])[CH2:7][CH:6]([CH3:8])[CH2:5][CH2:4][CH:3]1[CH2:9][OH:10]

Participants

4

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 212637402,2,4-Trimethyl-1-cyclohexanecarbaldehyde

Product 1

HCID 21263744HCID 21263744, compoundYield 92%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The procedure described in the above Example 3 was repeated, using 20 g (0.13 mole) of 2,2,4-trimethyl-1-cyclohexanecarbaldehyde and 1.7 g (45 mmole) of LiAlH4 in 200 ml of diethyl ether. Distillation at 50°/0.5 hPa afforded 18.6 g (92%) of pure product, composed of about 90% of trans and 10% of cis-isomer.

Workup

  1. distillationDistillation at 50°/0.5 hPa

Sources & evidence

ORD record
ord-82dd95d5a65649ac9dd5599c2e64de51
Source dataset
uspto-grants-2001_01
Patent number
US06177400B1

Reaction notes

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