Methanol → 2-Hexyloxirane

HRID 566869Notes

Reaction equation

HRID 566869 reaction equation
[C:1]1([CH3:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:8][OH:9]>C(Cl)(Cl)Cl.O>[O:9]1[CH:2]([CH2:3][CH2:4][CH2:5][CH2:6][CH2:1][CH3:7])[CH2:8]1

Participants

5

Reactant 2

HCID 887MethanolHCID 1140Toluene

Product 1

HCID 181262-Hexyloxirane

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 6212ChloroformSolvent

Procedure

To a solution of 0.50 g of sixth generation PAMAM in 5 ml of methanol was added 0.56 g of epoxyoctane. After 6 days at room temperature, the solvent was evaporated in vacuo to give 0.80 g of colorless oil. The material was soluble in chloroform, toluene or methanol, but not soluble in water. The 13C-NMR spectrum was in accord with a dendrimer with C-8 alkyl groups attached to its terminal amines.

Sources & evidence

ORD record
ord-0d30c46c6c6a491cbb2ac25819cf23c3
Source dataset
uspto-grants-2001_01
Patent number
US06177414B1

Reaction notes

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