HCID 70213398, compound → HCID 70215948, compound

Participants

Reaction Steps

A solution of the crude alcohol in 60 mL of THF and 18 mL of 2 M liCl was refluxed for 24 h. After the solution was concentrated to about 20 mL and diluted with about 50 mL of ether, it was washed with 50 mL of water, 50 mL of saturated NaCHO3 2 and 50 mL of brine respectively. The solution was dried over anhydrous MgSO4 and concentrated to afford crude 3α,12α-dihydroxy-24,24-dimethyl-5α-cholan-24-ol.

Provenance & Evidence