HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 9955004, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | HCID 10503986 | HCID 10503986 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 9955004 | HCID 9955004 | 43.4% |
Reaction Steps
A mixture of 956 mg (2.1 mmol) of ((3-(2-amino-1,2-dioxoethyl)-1-((1,1′-biphenyl)-3-ylmethyl)-2-methyl-1H-indol-4-yl)oxy)acetic acid methyl ester is hydrolyzed at reflux in 10 mL of 1N NaOH and 20 mL of MeOH to give 403 mg (41% yield) of ((3-(2-amino-1,2-dioxoethyl)-1-((1,1′-biphenyl)-3-ylmethyl)-2-methyl-1H-indol-4-yl)oxy)acetic acid, sodium salt, mp, greater than 265° C. Analyses for C26H21N2O5Na:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06177426B1 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-f41c907edfe244cba5fdf026918ebc7c |
| Source note | uspto-grants-2001_01 |