HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Hydroxyphenyl)boronic acid → 6-(2-Hydroxyphenyl)-6'-(2-hydroxy-4-methylphenyl)-2,2'-bipyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Hydroxyphenyl)boronic acid | HCID 2773454 | — |
| Reactant | 6-Bromo-6'-(2-hydroxy-4-methylphenyl)-2,2'-bipyridine | HCID 135854288 | — |
| Product | 6-(2-Hydroxyphenyl)-6'-(2-hydroxy-4-methylphenyl)-2,2'-bipyridine | HCID 135673416 | 68% |
Reaction Steps
6-(2-Hydroxyphenyl)-6′-(2-hydroxy-4-methylphenyl)-2,2′-bipyridine was prepared from 6-bromo-6′-(2-hydroxy-4-methylphenyl)-2,2′-bipyridine and 2-hydroxyphenylboronic acid in 68% yield using method F; δH [2H6]-DMSO 13.55,(1H, b), 13.39,(1H, b), 8.38-8.32,(4H, m), 8.30-8.20,(4H, m), 8.13,(3H, d), 8.03,(1H, d), 7.37,(1H, t), 7.00,(2H, m), 6.81,(2H, m), 2.30,(3H, s); MS 355 (MH)+; HPLC retention time (system 1) 4.34 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06177419B1 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-37dfd2a269ce4ba9a331f23f6907ad05 |
| Source note | uspto-grants-2001_01 |