HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Hydroxyphenyl)boronic acid → 6-(2-Hydroxyphenyl)-6'-(2-hydroxy-3-methoxyphenyl)-2,2'-bipyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Hydroxyphenyl)boronic acid | HCID 2773454 | — |
| Reactant | 6-Bromo-6'-(2-hydroxy-3-methoxyphenyl)-2,2'-bipyridine | HCID 135854286 | — |
| Product | 6-(2-Hydroxyphenyl)-6'-(2-hydroxy-3-methoxyphenyl)-2,2'-bipyridine | HCID 135456007 | 39% |
Reaction Steps
6-(2-Hydroxyphenyl)-6′-(2-hydroxy-3-methoxyphenyl)-2,2′-bipyridine was prepared from 6-bromo-6′-(2-hydroxy-3-methoxyphenyl)-2,2′-bipyridine and 2-hydroxyphenyl boronic acid in 39% yield using method F; δH [2H6]-DMSO 13.48,(1H, b), 13.38,(1H, b), 8.33,(2H, m), 8.23, (2H, t), 8.17,(2H, d), 8.13,(1H, d), 7.70,(2H, d), 7.37,(1H, t), 7.09,(1H, d), 7.02,(1H, d), 6.94,(1H, t), 3.84,(3H, s); MS 371 (MH)+; HPLC retention time (system 1) 4.03 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06177419B1 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-f236adab9c7f4faca3ef30f5277b7cc4 |
| Source note | uspto-grants-2001_01 |