Chloroform → HCID 87667667, compound

HRID 566958Notes

Reaction equation

HRID 566958 reaction equation
[C:1]1(=[O:7])[O:6][C:4](=[O:5])C=[CH:2]1.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1.[Cl:26]Cl.[CH:28]([Cl:31])(Cl)Cl>>[Cl:26][C@H:2]1[C@H:28]([Cl:31])[C:4](=[O:5])[O:6][C:1]1=[O:7]

Participants

5

Reactant 4

HCID 6212ChloroformHCID 7187Benzoyl PeroxideHCID 7923Maleic AnhydrideHCID 24526Chlorine

Product 1

HCID 87667667HCID 87667667, compoundYield 65%

Procedure

A solution of maleic anhydride (10.6 g, 108 mmol) and benzoyl peroxide (5 mg, 0.02 mmol) in CHCl3 (250 mL) was saturated with chlorine gas and the resulting bright yellow solution was stirred for 5 h at rt. Residual chlorine was removed with a stream of nitrogen and the reaction mixture was partially concentrated. Four crops of the white, solid title product were obtained by filtration (11.9 g, 65% yield): mp 90-92° C.

Workup

  1. customResidual chlorine was removed with a stream of nitrogen
  2. concentrationthe reaction mixture was partially concentrated

Sources & evidence

ORD record
ord-fd0e418f6ba14bfb911a708ef865828f
Source dataset
uspto-grants-2001_01
Patent number
US06177445B1

Reaction notes

Loading…