Dimethylformamide → HCID 21264502, compound

Participants

Reaction Steps

To a solution of 2-hydroxy-3-nitropyridine (30.5 mmol) in DMF (20 ml), cesium carbonate (45.7 mmol) and allyl bromide (3.15 mL, 35.6 mmol) were added. The reaction mixture was stirred at room temperature for 18 hours, then it was partitioned between ethyl acetate and water. The combined organic phase was dried and concentrated to give the desired product (5.85 g, 94%). EI-MS m/z 205 (M+).

Provenance & Evidence