HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyloxyamine hydrochloride → 2-Benzyloxy-5-bromo-benzo[de]isoquinoline-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyloxyamine hydrochloride | HCID 102312 | — |
| Reactant | 5-Bromobenzo[de]isochromene-1,3-dione | HCID 3907491 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 2-Benzyloxy-5-bromo-benzo[de]isoquinoline-1,3-dione | HCID 22623899 | 89.1% |
Reaction Steps
O-Benzyl hydroxylamine hydrochloride (0.9 g, 5.6 mmol) and 3-bromo-1,8-naphthalic anhydride (1.3 g, 4.7 mmol, from Example N) were reacted in pyridine (30 mL) following the procedure of Example D to give 1.6 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06177423B1 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-03ec6581c64c40e6a9e19c9659ee0cf9 |
| Source note | uspto-grants-2001_01 |