HCID 21264532, compound → HCID 17786841, compound

Participants

Reaction Steps

7.2 g (18.5 mmol) of N-[6-benzyloxy-2,2-dimethylchroman-4-yl]-N-methylethanesulfonamide were dissolved in 150 ml of THF/methanol (1:1) and hydrogenated in a shaking duck using Pd/carbon. After absorption of hydrogen was complete, the catalyst was filtered off with suction, the filtrate was concentrated and the residue was crystallized using diisopropyl ether, 5.0 g, m.p. 160-162° C.

Provenance & Evidence