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HRID56707

反应详情

EQUATION

反应方程式

HRID 56707 的结构方程式

REACTANTS

反应物

2
结构：CC(Br)C(=O)O
HCID11729

2-Bromopropionic acid

C3H5BrO2

结构：O=c1cc(-c2cc(Cl)ccc2C(F)F)c(Cl)c[nH]1
HCID117605586

未命名化合物

PRODUCTS

生成物

1
结构：CC(C(=O)O)n1cc(Cl)c(-c2cc(Cl)ccc2C(F)F)cc1=O
HCID117622899

未命名化合物

PROCEDURE

实验过程

118 mg (0.41 mmol) of 5-chloro-4-[5-chloro-2-(difluoromethyl)phenyl]pyridin-2(1H)-one and 1.5 eq. of 2-bromopropanoic acid (racemate) were reacted according to General Method 4A at 35° C. Yield: 112 mg (76% of theory)

WORKUP

后处理

  1. customaccording to General Method 4A at 35° C