Carbonic acid, bis(1,1-dimethylethyl) ester → HCID 21264560, compound

HRID 567085Notes

Reaction equation

HRID 567085 reaction equation
[CH3:1][NH:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][NH2:11])=[CH:5][CH:4]=1.[C:12]([O:16][C:17](=O)[O:18]C(C)(C)C)([CH3:15])([CH3:14])[CH3:13]>>[CH3:1][NH:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][NH:11][C:17](=[O:18])[O:16][C:12]([CH3:15])([CH3:14])[CH3:13])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 10219638Carbonic acid, bis(1,1-dimethylethyl) esterHCID 21264568HCID 21264568, compound

Product 1

HCID 21264560HCID 21264560, compoundYield 94.6%

Procedure

2.03 g of 2-(4-methylaminophenyl)ethylamine and 3.20 g of di-t-butylcarbonate were subjected to an acylation reaction to obtain 3.20 g of t-butyl 2-(4-methylaminophenyl)ethylcarbamate.

Sources & evidence

ORD record
ord-23cbcc5b6357448a9095ee9d39552d90
Source dataset
uspto-grants-2001_01
Patent number
US06177454B1

Reaction notes

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