Ethanol → HCID 21692314, compound

HRID 567187Notes

Reaction equation

HRID 567187 reaction equation
[CH2:1]([SH:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[CH3:14][O-:15].[Na+].[CH2:17]([OH:19])[CH3:18]>>[CH2:1]([S:13][CH2:18][CH:17]([OH:19])[CH2:14][O:15][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

4

Reactant 3

HCID 702Ethanol2×HCID 81951-DodecanethiolHCID 10942334Sodium Methoxide

Product 1

HCID 21692314HCID 21692314, compound

Procedure

After dissolving in 30 ml ethanol this oil was admixed with a mercaptide solution which had previously been prepared by reacting 1.94 ml 1-dodecylmercaptan in 20 ml ethanol with sodium methylate. After stirring overnight at room temperature, the solvent was removed by distillation, the residue was taken up in dichloromethane, washed twice with water and the organic phase was evaporated. The residue was purified by chromatography on silica gel 60 using ether/isohexane 1:5 as the eluant. Yield 3.9 g.

Workup

  1. customhad previously been prepared
  2. customthe solvent was removed by distillation
  3. washwashed twice with water
  4. customthe organic phase was evaporated
  5. customThe residue was purified by chromatography on silica gel 60 using ether/isohexane 1:5 as the eluant

Sources & evidence

ORD record
ord-f76aae65993f4b1b8e4ee1519c1bf8c6
Source dataset
uspto-grants-2001_01
Patent number
US06177469B1

Reaction notes

Loading…