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HRID56734

反应详情

EQUATION

反应方程式

HRID 56734 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)c1ccc(N)cc1
HCID233272

Benzoic acid, 4-amino-, 1,1-dimethylethyl ester

C11H15NO2

结构：CC(C(=O)O)n1cc(C(F)(F)F)c(-c2cc(Cl)ccc2C#N)cc1=O
HCID117622720

未命名化合物

PRODUCTS

生成物

1
结构：CC(C(=O)Nc1ccc(C(=O)OC(C)(C)C)cc1)n1cc(C(F)(F)F)c(-c2cc(Cl)ccc2C#N)cc1=O
HCID117622568

未命名化合物

PROCEDURE

实验过程

515 mg (purity 51%, 0.71 mmol) of 2-[4-(5-chloro-2-cyanophenyl)-2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl]propanoic acid (racemate) and 1.2 eq. of tert-butyl 4-aminobenzoate were reacted according to General Method 5A. Yield: 251 mg (purity 79%, 51% of theory)