HCID 15480961, compound → HCID 15480962, compound

Participants

Reaction Steps

A solution of ethyl 5-(2-dimethylaminoethyl)-3-oxo-1, 2,3,5-tetrahydropyrido[1,2-a]benzimidazole-4-carboxylate (1.0 g, 3 mmol) in ethanol (40 mL) and 10 M aqueous NaOH (20 ml) is heated at reflux for 2 h. The reaction mixture is cooled and the layers separated. The upper layer is diluted with ether (100 mL), washed with water (20 mL), dried, and concentrated to yield 5-(2-dimethylaminoethyl)-3-oxo-1,2,3,5-tetrahydropyrido [1,2-a]benzimidazole.

Provenance & Evidence