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HRID56739

反应详情

EQUATION

反应方程式

HRID 56739 的结构方程式

REACTANTS

反应物

2
结构：O=[N+]([O-])c1ccc(Cl)cc1Br
HCID9856124

2-bromo-4-chloro-1-nitrobenzene

C6H3BrClNO2

结构：COc1cc(B(O)O)c(OC)cn1
HCID74890663

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(-c2cc(Cl)ccc2[N+](=O)[O-])c(OC)cn1
HCID117605401

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)c1cc(C(C)C)c(-c2ccccc2P(C2CCCCC2)C2CCCCC2)c(C(C)C)c1.NCCc1[c-]cccc1.[Cl][Pd+]
催化剂HCID54751079

Chloropalladium(1+) 2-(2-aminoethyl)benzen-1-ide--dicyclohexyl[2',4',6'-tri(propan-2-yl)[1,1'-biphenyl]-2-yl]phosphane (1/1/1)

C41H59ClNPPd

PROCEDURE

实验过程

215 mg (purity 85%, 1.0 mmol) of 2,5-dimethoxypyridin-4-ylboronic acid and 236 mg (1.0 mmol) of 2-bromo-4-chloro-1-nitrobenzene in the presence of XPhos precatalyst were reacted according to General Method 2B. Yield: 124 mg (purity 93%, 39% of theory)