Pyridinium hydrochloride → 4-(5-Chloro-2-nitrophenyl)-5-methoxy-2(1h)-pyridinone

HRID 56740Notes

Reaction equation

HRID 56740 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:18]([O-:20])=[O:19])=[C:6]([C:8]2[C:13]([O:14][CH3:15])=[CH:12][N:11]=[C:10]([O:16]C)[CH:9]=2)[CH:7]=1.Cl.[NH+]1C=CC=CC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:18]([O-:20])=[O:19])=[C:6]([C:8]2[C:13]([O:14][CH3:15])=[CH:12][NH:11][C:10](=[O:16])[CH:9]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 21584435Pyridinium hydrochlorideHCID 1176054014-(5-Chloro-2-nitrophenyl)-2,5-dimethoxypyridine

Product 1

HCID 1176226574-(5-Chloro-2-nitrophenyl)-5-methoxy-2(1h)-pyridinone

Procedure

124 mg (purity 93%, 0.39 mmol) of 4-(5-chloro-2-nitrophenyl)-2,5-dimethoxypyridine and pyridinium hydrochloride were reacted according to General Method 3A. Yield: 115 mg (purity 85%, 89% of theory)

Sources & evidence

ORD record
ord-9c6f7f7830724d2fbc1dc0224f6e5330
Source dataset
uspto-grants-2016_09
Patent number
US09434690B2

Reaction notes

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