3-Ethoxy-4-ethoxycarbonylphenylacetic acid → Ethyl 2-ethoxy-4-[N-{1-(5-chloro-2-piperidino-phenyl)-1-propyl}-aminocarbonylmethyl]-benzoate

HRID 567572Notes

Reaction equation

HRID 567572 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:12]2[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]2)=[C:6]([CH:8]([NH2:11])[CH2:9][CH3:10])[CH:7]=1.[CH2:18]([O:20][C:21]1[CH:22]=[C:23]([CH2:32][C:33](O)=[O:34])[CH:24]=[CH:25][C:26]=1[C:27]([O:29][CH2:30][CH3:31])=[O:28])[CH3:19]>>[CH2:18]([O:20][C:21]1[CH:22]=[C:23]([CH2:32][C:33]([NH:11][CH:8]([C:6]2[CH:7]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=2[N:12]2[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[CH2:9][CH3:10])=[O:34])[CH:24]=[CH:25][C:26]=1[C:27]([O:29][CH2:30][CH3:31])=[O:28])[CH3:19]

Participants

3

Reactant 2

HCID 101312123-Ethoxy-4-ethoxycarbonylphenylacetic acidHCID 545660581-(5-Chloro-2-piperidino-phenyl)-1-propylamine

Product 1

HCID 21261882Ethyl 2-ethoxy-4-[N-{1-(5-chloro-2-piperidino-phenyl)-1-propyl}-aminocarbonylmethyl]-benzoate

Procedure

Prepared from 1-(5-chloro-2-piperidino-phenyl)-1-propylamine and 3-ethoxy-4-ethoxycarbonyl-phenylacetic acid.

Sources & evidence

ORD record
ord-113c30f549fd4d1791cba0b16602cf2d
Source dataset
uspto-grants-2001_01
Patent number
USRE037035E1

Reaction notes

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