1-(2-Piperidino-phenyl)-1-butylamine → ethyl 2-hydroxy-4-[N-{1-(2-piperidinophenyl)-1-butyl}-aminocarbonylmethyl]-benzoate
Reaction equation
[N:1]1([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[CH:13]([NH2:17])[CH2:14][CH2:15][CH3:16])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:18]([O:20][C:21]([C:23]1[CH:28]=[CH:27][C:26]([CH2:29][C:30](O)=[O:31])=[CH:25][C:24]=1[OH:33])=[O:22])[CH3:19]>>[OH:33][C:24]1[CH:25]=[C:26]([CH2:29][C:30]([NH:17][CH:13]([C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[N:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)[CH2:14][CH2:15][CH3:16])=[O:31])[CH:27]=[CH:28][C:23]=1[C:21]([O:20][CH2:18][CH3:19])=[O:22]Participants
3
Procedure
Prepared from 1-(2-piperidino-phenyl)-1-butylamine and 4-ethoxycarbonyl-3-hydroxy-phenylacetic acid.
Sources & evidence
- ORD record
- ord-f33765f39692434f9d51caacd1b513d5
- Source dataset
- uspto-grants-2001_01
- Patent number
- USRE037035E1
Reaction notes
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