Hydrazine → HCID 18399544, compound

HRID 567713Notes

Reaction equation

HRID 567713 reaction equation
[NH2:1][NH2:2].[C:3]([C:11]1[C:16]([C:17]([OH:19])=O)=[CH:15][CH:14]=[CH:13][N:12]=1)(=O)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1>>[C:4]1([C:3]2[C:11]3[C:16](=[CH:15][CH:14]=[CH:13][N:12]=3)[CH:17]([OH:19])[NH:2][N:1]=2)[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

3

Reactant 2

HCID 9321HydrazineHCID 8245992-benzoylnicotinic acid

Product 1

HCID 18399544HCID 18399544, compound

Procedure

A 3M ethanolic solution of hydrazine (20 ml, 60 mmol) is added to an ethanolic solution of 2-benzoyl-3-pyridine carboxylic acid (4.54 g, 20 mmol), and the mixture is stirred at room temperature for 5-24 hours. Precipitation yields 4-phenyl-1,2-dihydro-5-azaphthalazin-1-ol.

Workup

  1. customPrecipitation

Sources & evidence

ORD record
ord-16280f94d332487288f3473d25ac5dea
Source dataset
uspto-grants-2001_01
Patent number
US06180629B2

Reaction notes

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