HCID 86756334, compound → Sampatrilat

Participants

Reaction Steps

(S,S,S)-N-(1-[2-Carboxy-3-(N2-mesyllysylamino)propyl]-1-cyclopentylcarbonyl)tyrosine hydrate (the δ-form, see Preparation 2) (20.0 g) was dissolved in water (250 ml) at room temperature and the clear solution frozen using a solid carbon dioxide/acetone bath. The solid mass was freeze dried to yield the title compound as a white solid (19.0 g). This material decomposed slowly over the temperature range 155-170° C.

Provenance & Evidence