HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-methylphenyl isocyanate → N-(2-hydroxy-4-nitrophenyl) N'-(2-chloro 6-methylphenyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-methylphenyl isocyanate | HCID 268123 | — |
| Reactant | 2-Amino-5-Nitrophenol | HCID 4984721 | — |
| Product | N-(2-hydroxy-4-nitrophenyl) N'-(2-chloro 6-methylphenyl)urea | HCID 19595671 | 29% |
Reaction Steps
The urea was prepared from 2-hydroxy 4-nitro aniline (500 mg, 3.24 mmol) and 2-chloro 6-methyl phenylisocyanate by general Method B. It was purified by dilution with methylene chloride and precipitation with hexane. Filtering afforded the desired compound(0.31 g, 29%). EI-MS m/z 322(M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06180675B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-ff2d36b482c044be807d0ad3f35e6e9c |
| Source note | uspto-grants-2001_01 |