2,4-Dibromophenyl isocyanate → HCID 22011336, compound

HRID 567997Notes

Reaction equation

HRID 567997 reaction equation
[N+:1]([C:4]1[CH:10]=[CH:9][C:7]([NH2:8])=[C:6]([OH:11])[CH:5]=1)([O-:3])=[O:2].[Br:12][C:13]1[CH:18]=[C:17]([Br:19])[CH:16]=[CH:15][C:14]=1[N:20]=[C:21]=[O:22]>>[OH:11][C:6]1[CH:5]=[C:4]([N+:1]([O-:3])=[O:2])[CH:10]=[CH:9][C:7]=1[NH:8][C:21]([NH:20][C:14]1[CH:15]=[CH:16][C:17]([Br:19])=[CH:18][C:13]=1[Br:12])=[O:22]

Participants

3

Reactant 2

HCID 46491272,4-Dibromophenyl isocyanateHCID 49847212-Amino-5-Nitrophenol

Product 1

HCID 22011336HCID 22011336, compoundYield 39.4%

Procedure

The urea was prepared from 4-nitro 2-hydroxy aniline(308 mg, 2 mmol) and 2,4-dibromophenylisocyanate(2 mmol) by general Method B. It was purified by dilution with methylene chloride and precipitation with hexane. Filtering afforded the title compound(0.34 g, 39%). EI-MS m/z 430(M+H)+.

Workup

  1. customIt was purified by dilution with methylene chloride and precipitation with hexane
  2. filtrationFiltering

Sources & evidence

ORD record
ord-8dcc06d3ac9b43c1bb2509c9050f2d04
Source dataset
uspto-grants-2001_01
Patent number
US06180675B2

Reaction notes

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