Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Phenoxybenzoic acid | HCID 75237 | — |
| Reactant | P,P-Diphenylphosphinic azide | HCID 199401 | — |
| Reactant | 2-Amino-5-Nitrophenol | HCID 4984721 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 9950992 | HCID 9950992 | — |
Reaction Steps
The urea was synthesized by the treatment of 2-phenoxyphenylcarboxylic acid(2 mmol,) with diphenyl phosphoryl azide(0.475 mL) and triethyl amine(0.14 mL) in DMF at 80° C. after 24 hours the 2-amino 5-nitrophenol (1 equiv.) was added. The reaction was heated for 24 hours at 80° C. The reaction product was oiled out with hexane. The residue was dissolved in methanol and the solid was precipitated out with water.(180 mg, 24%) EI-MS m/z 364(M−H)−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06180675B2 |
|---|
| Source dataset | uspto-grants-2001_01 |
|---|
| ORD ID | ord-34cfec015d1447a4b662fa11d7320fed |
|---|
| Source note | uspto-grants-2001_01 |
|---|
