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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 568010Generated: October 29, 2026

(1,1'-Biphenyl)-3-ol, 4-nitro- → 2-Amino-5-phenylphenol

https://huagongshe.com/reaction/568010

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-ol, 4-nitro-HCID 87437—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product2-Amino-5-phenylphenolHCID 20376—

Reaction Steps

A solution of 2-nitro 5-phenylphenol(1.2 g, 5.5 mmol) in methanol was treated with 10% Pd/C(1.2 g). The reaction mixture was flushed with hydrogen and allowed to stir overnight. The reaction mixture was filtered through celite and the filtrate was concentrated in vacuo to afford desired (1.01 g, 98%). EI-MS m/z 186(M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06180675B2
Source datasetuspto-grants-2001_01
ORD IDord-ae3410ffb02b4a9a92724183a1fd4f28
Source noteuspto-grants-2001_01