2-Bromophenyl isocyanate → N-(2-(benzylsulfonylamino)phenyl) N'-(2-bromophenyl)urea

HRID 568024Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 568024
[CH2:1]([S:8]([NH:11][C:12]1[CH:18]=[CH:17][CH:16]=[CH:15][C:13]=1[NH2:14])(=[O:10])=[O:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[N:26]=[C:27]=[O:28]>>[CH2:1]([S:8]([NH:11][C:12]1[CH:18]=[CH:17][CH:16]=[CH:15][C:13]=1[NH:14][C:27]([NH:26][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=1[Br:19])=[O:28])(=[O:9])=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

3

Edukt 2

HCID 1370972-Bromophenyl isocyanateHCID 167784432-(Benzylsulfonylamino)aniline

Produkt 1

HCID 54425527N-(2-(benzylsulfonylamino)phenyl) N'-(2-bromophenyl)ureaAusbeute 23,9 %

Versuchsvorschrift

The urea was synthesized from 2-(benzylsulfonylamino)aniline(1 mmol) and 2-bromophenylisocyanate(1 mmol) by general Method B. It was purified by dilution with methylene chloride and precipitation with hexane. Filtering afforded the desired compound(0.11 g, 23%). EI-MS m/z 460 (M+H)+.

Aufarbeitung

  1. customIt was purified by dilution with methylene chloride and precipitation with hexane
  2. filtrationFiltering

Quellen und Nachweise

ORD-Eintrag
ord-cf476b9b942e42698b90c538a6871775
Quelldatensatz
uspto-grants-2001_01
Patentnummer
US06180675B2

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