HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 21262974, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Benzyl mercaptan | HCID 7509 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3,4-Difluorobenzonitrile | HCID 587203 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21262974 | HCID 21262974 | 93.9% |
Reaction Steps
To a solution of 25 g of 3,4-difluorobenzonitrile in 100 ml of N,N-dimethylformamide is added 25 g of potassium carbonate and 22.3 g of benzylmercaptan. The mixture is stirred for 3 hours at room temperature and water is added. The crystals are filtered off, washed with water and pentane and dried to give 41 g of 4-benzylthio-3-fluorobenzonitrile in the form of crystals melting at 87° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06180651B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-65e1c352165144e1bef6a5a39d0e0249 |
| Source note | uspto-grants-2001_01 |