HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (S)-2-Amino-3-(4-benzyloxy-phenyl)-N-tert-butyl-propionamide monohydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (S)-2-amino-3-(4-benzyloxy-phenyl)-N-tert-butyl-propionamide | HCID 15517727 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | (S)-2-Amino-3-(4-benzyloxy-phenyl)-N-tert-butyl-propionamide monohydrochloride | HCID 69584616 | — |
Reaction Steps
To a solution of (S)-2-amino-3-(4-benzyloxy-phenyl)-N-tert-butyl-propionamide (Example 1, Step B) in ether was added excess amount of ethereal HCl. The solid formed was isolated via filtration, and subsequent drying under vacuum gave (S)-2-Amino-3-(4-benzyloxy-phenyl)-N-tert-butyl-propionamide monohydrochloride as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06180677B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-b22bb5d7cda54932be3672e3890583a7 |
| Source note | uspto-grants-2001_01 |