HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Dithionite → 1,3-Di-cyclopropyl-8-amino Xanthine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Dithionite | HCID 24489 | — |
| Reactant | 1,3-Di-cyclopropyl-8-nitro xanthine | HCID 9838492 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1,3-Di-cyclopropyl-8-amino Xanthine | HCID 9813621 | — |
Reaction Steps
1,3-Di-cyclopropyl-8-nitro xanthine (0.4 g, 0.0014 mol) was dissolved in methanol (20 ml) and treated with a sodium dithionite solution in water (0.5 g in 5 ml) at room temperature with stirring. After stirring for three hours the solvent was removed in vacuo, the residue taken up with dichloromethane and extracted with water (40 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06180791B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-8fc34d0938c940a3a98edba659c5d90d |
| Source note | uspto-grants-2001_01 |