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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 568141Generated: October 30, 2026

Pyrrolidine → 1,3-Di-n-butyl-8-pyrrolidinyl Xanthine

https://huagongshe.com/reaction/568141

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant1,3-Di-n-butyl-8-bromo XanthineHCID 10154489—
Product1,3-Di-n-butyl-8-pyrrolidinyl XanthineHCID 9902188—

Reaction Steps

The title compound was prepared from 1,3-di-n-butyl-8-bromo xanthine (1 g, 0.0029 ml) and pyrrolidine (0.041 g, 0.0057 mol) using an analogous procedure to that described in Example 19. The title product was obtained as a crystalline solid, m.pt. >250° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06180791B2
Source datasetuspto-grants-2001_01
ORD IDord-ca80269a77bc468e8080262b50bef80a
Source noteuspto-grants-2001_01