Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 568144Generated: October 31, 2026

Piperidine → 1,3-Di-cyclohexylmethyl-8-piperidinyl Xanthine

https://huagongshe.com/reaction/568144

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
Reactant1,3-Di-cyclohexylmethyl-8-bromo xanthineHCID 10202505—
Product1,3-Di-cyclohexylmethyl-8-piperidinyl XanthineHCID 10113349—

Reaction Steps

The title compound was prepared from 1,3-di-cyclohexylmethyl-8-bromo xanthine (0.7 g, 0.0017 mol) and piperidine (0.28 g, 0.003 mol) using an analogous procedure to that described in Example 19. The title product was obtained as a crystalline solid, m.pt. 266° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06180791B2
Source datasetuspto-grants-2001_01
ORD IDord-3d912d1f9a3648fc908542d1eba28714
Source noteuspto-grants-2001_01