HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 1-Bromo-4-(4-chlorophenyl)-3,3-dimethylbutan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 4-(4-Chlorophenyl)-3,3-dimethylbutan-2-one | HCID 12870632 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 1-Bromo-4-(4-chlorophenyl)-3,3-dimethylbutan-2-one | HCID 13286525 | 97.3% |
Reaction Steps
98.8 g (0.62 mol) of bromine are added dropwise to 130 g (0.62 mol) of 1-(4-chlorophenyl)-2,2-dimethyl-3-butanone in 1000 ml of chloroform at room temperature. The reaction mixture is subsequently stirred for 1 hour and is then concentrated. 174.7 g (97.3% of theory) of 4-bromo-1-(4-chlorophenyl)-2,2-dimethyl-3-butanone of refractive index nD20 1.5570 are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04728356 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-9db1c6f221d946089851c6bbf07fa8a3 |
| Source note | uspto-grants-1988_03 |