HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 568317Generated: October 26, 2026
Hydrochloric Acid → 1-Amino-4-(5'-amino-2'-methylphenylamino)-anthraquinone-2-sulphonic acid
https://huagongshe.com/reaction/568317
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1-Amino-4-bromo-9,10-dihydro-9,10-dioxo-2-anthracenesulfonic acid | HCID 22628 | — |
| Reactant | N-(3-amino-4-methylphenyl)acetamide | HCID 22865 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 1-Amino-4-(5'-amino-2'-methylphenylamino)-anthraquinone-2-sulphonic acid | HCID 20150048 | — |
Reaction Steps
38.2 Parts 1-amino-4-bromoanthraquinone-2-sulphonic acid are dissolved in 200 parts water/100 parts i-propanol and the pH adjusted to 8.5-9.0 with sodium carbonate. After addition of 18 parts 4-acetylamino-2-aminotoluene the mixture is warmed to 80° C. and treated with 1 part cuprous chloride and 12 parts sodium carbonate. After 4 hours the reaction is over. Finally 25 parts 30% hydrochloric acid are added to the reaction mixture, which is then heated to reflux. After 18 hours the suspension is cooled to room temperature, filtered and washed with 1% hydrochloric acid, to give 1-amino-4-(5'-amino-2'-methylphenylamino)-anthraquinone-2-sulphonic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04728464 |
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| Source dataset | uspto-grants-1988_03 |
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| ORD ID | ord-f7fe5edc58404c08adc817af9b395f9c |
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| Source note | uspto-grants-1988_03 |
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