HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Trans-N-(4-bromo-2-methylphenyl)-3-ethoxypropenamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 4-Bromo-2-methylaniline | HCID 11423 | — |
| Reactant | 3-Ethoxyacryloyl chloride | HCID 5325500 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | Trans-N-(4-bromo-2-methylphenyl)-3-ethoxypropenamide | HCID 14221021 | — |
Reaction Steps
Trans-3-ethoxypropenoyl chloride (0.74 g) was added at 0° to a stirred solution of 4-bromo-2-methylaniline (0.93 g) in pyridine (10 cm3). After 0.5 hours water (40 cm3) was added, the solid material was filtered off, washed with water (30 cm3) and dried. The product was recrystallised from ethyl acetate to afford trans-N-(4-bromo-2-methylphenyl)-3-ethoxypropenamide, m.p. 163°-164°, (1.3 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04728654 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-59ac6bb072e24b90ba5395cc648529d7 |
| Source note | uspto-grants-1988_03 |