Nitric Acid → HCID 14450250, compound

HRID 568381Notes

Reaction equation

HRID 568381 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([N:8]2[CH:12]=[N:11][N:10]=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[N+:13]([O-])([OH:15])=[O:14]>>[CH3:1][C:2]1[CH:3]=[C:4]([N:8]2[CH:12]=[N:11][N:10]=[N:9]2)[CH:5]=[CH:6][C:7]=1[N+:13]([O-:15])=[O:14]

Participants

3

Reactant 2

HCID 944Nitric AcidHCID 14450259HCID 14450259, compound

Product 1

HCID 14450250HCID 14450250, compound

Procedure

1-(3-Methylphenyl)tetrazole (11.3 g) was cautiously added at 0° to fuming nitric acid (100 cm3) with stirring and the solution was then warmed on a steam bath for 5 minutes. The cooled solution was poured onto ice (200 g), and the solid material was filtered off, washed with water (100 cm3) and dried. Recrystallisation from ethyl acetate afforded 1-(3-methyl-4-nitrophenyl)tetrazole, m.p. 166°-168° (9.4 g).

Workup

  1. temperaturethe solution was then warmed on a steam bath for 5 minutes
  2. additionThe cooled solution was poured onto ice (200 g)
  3. filtrationthe solid material was filtered off
  4. washwashed with water (100 cm3)
  5. customdried
  6. customRecrystallisation from ethyl acetate

Sources & evidence

ORD record
ord-0b1387257e8a42f39f020ce9e46ecdbc
Source dataset
uspto-grants-1988_03
Patent number
US04728653

Reaction notes

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