Benzyl Chloride → HCID 20150151, compound

HRID 568451Notes

Reaction equation

HRID 568451 reaction equation
[CH2:1](Cl)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:9]([N:11]1[CH2:16][CH2:15][N:14]([C:17]2[N:18]=[C:19]([N:28]3[CH2:33][CH2:32][O:31][CH2:30][CH2:29]3)[C:20]3[N:26]=[CH:25][N:24]=[C:23]([SH:27])[C:21]=3[N:22]=2)[CH2:13][CH2:12]1)=[O:10]>[OH-].[Na+]>[CH2:1]([S:27][C:23]1[C:21]2[N:22]=[C:17]([N:14]3[CH2:15][CH2:16][N:11]([CH:9]=[O:10])[CH2:12][CH2:13]3)[N:18]=[C:19]([N:28]3[CH2:29][CH2:30][O:31][CH2:32][CH2:33]3)[C:20]=2[N:26]=[CH:25][N:24]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 7503Benzyl ChlorideHCID 178521669HCID 178521669, compound

Product 1

HCID 20150151HCID 20150151, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

0.7 ml (0.006 mol) of benzyl chloride were added dropwise to a solution of 1.8 gm (0.005 mol) of 2-(N-formylpiperazino)-8-mercapto-4-morpholino-pyrimido-[5,4-d]-pyrimidine (m.p. 250°-255° C.) in about 60 ml of 0.1N sodium hydroxide. After stirring the mixture at room temperature for one hour, the precipitated reaction product was suction-filtered off, washed with water and dried.

Workup

  1. customthe precipitated reaction product
  2. filtrationwas suction-filtered off
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-11bb952334334e898d79b3b1f847f719
Source dataset
uspto-grants-1988_03
Patent number
US04728646

Reaction notes

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