1-Piperazinecarboxaldehyde → HCID 12817112, compound

HRID 568478Notes

Reaction equation

HRID 568478 reaction equation
[NH2:1][C:2]1[C:7]2[N:8]=[C:9](Cl)[N:10]=[C:11]([N:12]3[CH2:17][CH2:16][S:15](=[O:18])[CH2:14][CH2:13]3)[C:6]=2[N:5]=[CH:4][N:3]=1.[CH:20]([N:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1)=[O:21]>>[NH2:1][C:2]1[C:7]2[N:8]=[C:9]([N:25]3[CH2:26][CH2:27][N:22]([CH:20]=[O:21])[CH2:23][CH2:24]3)[N:10]=[C:11]([N:12]3[CH2:17][CH2:16][S:15](=[O:18])[CH2:14][CH2:13]3)[C:6]=2[N:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 821911-PiperazinecarboxaldehydeHCID 12816997HCID 12816997, compound

Product 1

HCID 12817112HCID 12817112, compound

Procedure

This compound was prepared analogous to Example 181 from 8-amino-2-chloro-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine (m.p.: 270°-272° C., decomp.) and N-formyl-piperazine at 130° C.

Sources & evidence

ORD record
ord-d7cd17673061483787d98e411511daf3
Source dataset
uspto-grants-1988_03
Patent number
US04728646

Reaction notes

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